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Blood Transfusion Science Question Paper

Blood Transfusion Science

Course:Diploma In Medical Laboratory Science

Institution: Kenya Medical Training College question papers

Exam Year:2011

KENYA MEDICAL LABORATORY TECHNICIANS AND TECHNOLOGISTS BOARD
REGISTRATION EXAMINATIONS
DIPLOMA LEVEL
THEORY PAPER II
TIME ALLOWED: 2HRS TIME: 2.00PM-4.00PM
DATE: 7TH NOVEMBER, 2011

BLOOD TRANSFUSION SCIENCE

SECTION A: MULTIPLE CHOICE QUESTIONS (20 MARKS)
1. ANSWER ALL QUESTIONS
2. WRITE THE CORRECT CHOICES IN THE ANSWER BOOKLET
3. AVOID GUESSWORK, 0.5 MARK WILL BE DEDUCTED FROM THE TOTAL SCORE FOR EVERY WRONG ANSWER

1. When the allelic genes are alike, that person is said to be:
a) Heterozygous
b) Hemizygous
c) Recessive
d) Homozygous

2. 22% Bovine albumin is added to a test in order to:
a) Lower the di-electric constant
b) Increase the repulsion between the red cells
c) Increase the zeta-potential
d) Decrease the zeta-potential

3. Pre-treatment of red blood cells with enzymes:
a) Increases the charged particles
b) Exposes the antigenic sites on the Rbcs
c) Digests the red blood cells membrane exposing the antibodies
d) Preserves antigenic sites

4. The following parents can give rise to offsprings of all the four ABO blood groups:
a) Group A and B parents
b) Group B and AB parents
c) Group A and AB parents
d) Group AB and O parents

5. The precursor substance is first acted upon by:
a) A gene
b) O gene
c) B gene
d) H gene

6. Bombay phenotype individuals:
a) Have antigens A and B in their red blood cells
b) Have antibodies A and B only in serum
c) Lack ABO antibodies only in serum
d) Are universal recipients

7. An individual grouped as Du positive:
a) Is rhesus negative
b) Lacks all rhesus antigens
c) Is rhesus null phenotype
d) Is rhesus positive

8. A cross-match will:
a) Prevent immunization
b) Detect errors in ABO-typing
c) Guarantee normal survival of donors rbcs in the recipient
d) Not detect errors in ABO grouping

9. Rhogam:
a) Is a purified gamma D globulin
b) Is a purified gamma E globulin
c) Coats the maternal red bllod cells
d) Lyses the maternal red blood cells

10. Substances that are capable of reacting with antbodies but do not stimulate antibody formation are called:
a) Carrier molecules
b) Haptens
c) Immunogens
d) Carbohydrates

11. The best storage temperature for donated blood awaiting crossmatch is:
a) 0-10o C
b) 18-25o C
c) 20-24o C
d) 2-8o C

12. Rhesus null red cells:
a) React with all rhesus antibodies
b) React with anti-D only
c) Are commonly found in Africans
d) May exhibit stomatocytosis

13. Cells are washed to:
a) Make them clean
b) Avoid haemolysis
c) Remove unwanted proteins
d) Avoid agglutination

14. Anti H can be prepared from the following phytagglutinin:
a) Iberis amara
b) Dolichos biflorus
c) Vicia graminea
d) Ulex europeaus

15. The purpose of reverse grouping is to check:
a) Antigens in red blood cells
b) Agglutinins in serum
c) Agglutinins in plasma
d) Agglutinins in red blood cells

16. The following facts refers to complements:
a) Can be preserved at -50 for a maximum of 48hrs
b) Can be destryed by heating at 56o C or above
c) Promote inflammatory response
d) Are not found in fresh normal plasma

17. Indirect coomb's test detects:
a) Maternal antibodies in HDNB
b) Paternal antibodies in HDNB
c) Foetal antigens
d) Maternal antigens

18. The most reliable grouping technique is:
a) Slide method
b) Micro-well method
c) Tile method
d) Tube method

19. Antihuman globulin is obtained from:
a) Immunized mothers
b) Bovine
c) Hybrid rabbit
d) Lectins

20. Pyrogens are mostly the common causes of:
a) Toxicity
b) Allergic reactions
c) Anaphylactic reactions
d) Febrile reactions

SECTION B: ESSAY QUESTIONS (30 MARKS)
1. ANSWER ALL QUESTIONS
2. BEGIN WITH ANY QUESTION BUT MAKE SURE YOU COMPLETE IT BEFORE ATTEMPTING THE NEXT

1. Explain five reasons for washing of red blood cells (RBCs) during cross-matching of blood for transfusion (10 marks)

2. Describe the conditions that would disqualify a potential blood donor (10 marks)

3. Discuss the different phases of the crossmatch technique (10 marks)

Blood Transfusion Science Question Paper

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