Aap 2303: Pharmacology And Pharmacognosy Question Paper

Aap 2303: Pharmacology And Pharmacognosy 

Course:Bachelor Of Science In Animal Health And Production

Institution: Jomo Kenyatta University Of Agriculture And Technology question papers

Exam Year:2012



JOMO KENYATTA UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
UNIVERSITY EXAMINATIONS 2012/2012
YEAR THREE FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF SCIENCE IN ANIMAL HEALTH, PRODUCTION AND PROCESSING
AAP 2303: PHARMACOLOGY AND PHARMACOGNOSY
DATE: AUGUST 2012 TIME: 2 HOURS
INSTRUCTIONS:
SECTION A IS COMPULSORY. ANSWER ANY TWO OTHER QUESTIONS IN SECTION B.

SECTION A – 30 MARKS (COMPULSORY)

QUESTION ONE

a. Define the following terms;
i. Pharmacokinetics [2 marks]
ii. Pharmacoeconomics [2 marks]
iii. Toxicology [2 marks]
iv. Tachyphylaxis [2 marks]
v. Prescription [2 marks]
b. Outline the main disadvantages of parenteral routes of drug administration. [5 marks]
QUESTION TWO
a. Explain the follwiong terms;
i. Pharmacognosy [3 marks]
ii. Carminative [3 marks]
iii. Antitussives [3 marks]
iv. Phytotherapy [2 marks]
b. Outline the fermentation process of drugs. [5 marks]
SECTION B (40 MARKS) ANSWER ONLY TWO QUESTIONS
QUESTION THREE (20 MARKS)
Discuss the general development of a ‘drug’ from a ‘medicinal plant’
QUESTION FOUR (20 MARKS)
Outline the biological origin, active principle and medicinal use of the following plants;
a. Qinghaosu (Artemisinin) plant
b. Opium (poppy) plant
c. Vinca plant
d. Taxol plant (pacific yew)
e. Datura plant
f. Pyrethrum plant
QUESTION FIVE (20 MARKS)
a. Outline the main components of a tablet. [6 marks]
b. Briefly outline ion-channel coupled receptors as a type of signal transduction giving relevant examples. [7 marks]
c. Explain the following terms;
i. Bioavailability [4 marks]
ii. Apparent volume of distribution. [3 marks]
QUESTION SIX (20 MARKS)
a. Define the following terms;
i. Plasma protein binding [2 marks]
ii. Therapeutic index [2 marks]
iii. Agonist [2marks]
iv. Plasma half-life [2 marks]
v. Loading dose [2 marks]

b. Discuss the main principles of drug action giving specific examples. [10 marks]






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