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Rad 2200: General Pathology Question Paper

Rad 2200: General Pathology 

Course:Bachelor Of Science In Radiography

Institution: Jomo Kenyatta University Of Agriculture And Technology question papers

Exam Year:2012



JOMO KENYATTA UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
UNIVERSITY EXAMINATIONS 2011/2012
FIRSTYEAR EXAMINATION FOR THE DEGREE OF BACHELOR OF SCIENCE IN RADIOGRAPHY
RAD 2200: GENERAL PATHOLOGY
DATE: AUGUST 2012 TIME: 2 HOURS
SECTION A Answer all
Each question has 4 items (a,b,d,d) and only one is correct.
Do not guess, half a mark will be deducted for every wrong response.
No mark for blank response
1. The following are causes of oedema except
a) Protein energy malnutrition
b) Anasarca
c) Liver cirrhosis
d) Renal insufficiency
2. The mechanisms of cell injury includethe following except
a) Acidosis which may interfere with enzyme function
b) Proliferation of the microtubules, filaments and actin
c) Loss of membrane integrity
d) Mitochondrial damage
3. Wound healing by primary intention
a) Acute inflammatory phase follows the remodeling phase
b) A lot of granulation tissue is laid out
c) Occurs in wounds that are clean
d) Occurs in high velocity gunshot wounds
4. The following are clinical signs of inflammation except
a) Loss of function
b) Redness
c) Pallor
d) Oedema

5. In regard to cellular adaptation
a) Hyperplasia is an increase in the size of the cells
b) Senile atrophy occurs particularly in the brain and heart
c) Chronic smoking can lead to hypertrophy of the respiratory epithelium
d) Hypertrophy is an increase in the number of cells
6. Which of the following is a granniomatons inflammation
a) Infection by plasmodium orale
b) Gonorrhea
c) Infection caused by cistosoma mansoni
d) Boils or furuncles
7. Morphological patterns of inflammation include
a) Liquefactive inflammation
b) Caseous inflammation
c) Fibrinousinflammation
d) Coagulative necrosis
8. The following are benign tumours expect
a) Neurofibroma
b) Chondroma
c) Fibroids
d) Clear cell caranoa of the kidney
9. In regard to cell death
a) Pyknosis, karyorrexis, and karyolysisoccurs in necrosis
b) In opoptosis the cell is enlarged
c) The plasma membrane is disrupted in apoptosis
d) Apoptosis elicits on inflammatory process in the surrounding tissue
10. Which of this is not a pattern of necrosis
a) Caseous necrosis
b) Fat necrosis
c) Suppurative necrosis
d) Liquefactive necrosis
11. Which is not an intracellular accumulation
a) Lipofuschin
b) Anthracolsis
c) Hemosiderin
d) Potassium
12. The following are quiescent cells except
a) Hepatocytes
b) Fibroblasts
c) Neurons
d) Kidney cells
13. The following are components of the virrchoris triad expect
a) Endothelial injury
b) Stasisand turbulence of the blood flow
c) Scarred heart valves causing altered blood flow
d) Laminar and blood flow
14. The following are components of haemostasis except
a) Blood vessels
b) Red blood cells
c) The intrinsic pathway
d) The endothelium
15. The following have anticoagulant effect expect
a) Protein C
b) Heparin
c) Activated platelets
d) Anti-thrombin III
16. Which of the following is not a common childhood tumor
a) Neuroblastoma
b) Wilms tumour
c) Burkitts lymphorra
d) Chondroma
17. Microbial and viral carainogens include
a) Hepatitis A
b) Staphylococcus aureus
c) Human papilloma virus
d) Treponema pallidum
18. Tumour metastasis occurs through
a) Faecal oral route
b) Blood transfusion
c) Hematogenous spread
d) Vertical spread
19. The coagulation screen includes all except
a) Peripheral blood film
b) Bleeding time
c) APTT/KCCT
d) Red blood counts
20. The role of prostaglandins in inflammation include
a) Vasoconstriction
b) Chemotaxis
c) Increased vascular permeability
d) Anaphylatoxin
SECTION B Answer all (6 Marks each)
21. Enumerate the methods of laboratory diagnosis of cancer
22. Compare and contrast benign and malignant tumours
23. Briefly describe gangrene
24. List the differences between apoptosis and necrosis
25. Briefly describe embolism
SECTION C Answer only one question (20 Marks)
26. Discuss thrombosis
27. Describe bone healing and outline the factors that affect wound healing
28. Describe the pathophysiology of acute inflammation and compare and contrast acute and chronic inflammation.






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