Dcmb 115: Introduction To Medical Biochemistry Question Paper
Dcmb 115: Introduction To Medical Biochemistry
Course:Medical Laboratory Sciences
Institution: Kenya Methodist University question papers
Exam Year:2012
KENYA METHODIST UNIVERSITY
END OF 2''ND ''TRIMESTER 2012(DAY) EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : MEDICAL LABORATORY SCIENCES
UNIT CODE : DCMB 115
UNIT TITLE : INTRODUCTION TO MEDICAL BIOCHEMISTRY
TIME : 3HOURS
INSTRUCTIONS: Answer ALL Questions in Section A
State whether true or false for each of the statements
No mark will be given/deducted for unanswered questions
One mark will be awarded for the correct answer
One mark will be deducted for the wrong answer
SECTION A (20marks)
QUESTION ONE
Ionic bonds
A. Are bonds formed between negatively and positively charged atoms
B. Are formed by sharing of electrons between two atoms
C. Are formed so that the constituent atoms can attain the octet
configuration
D. Are formed between hydrogen ions and negatively charged oxygen or
nitrogen atoms.
E. All the above
QUESTION TWO
The atomic number is
A. Equal to the number of electrons in a positively charged atom.
B. Equal to the number of protons
C. Equal to the mass number
D. Equal to the number of protons plus neutrons
E. Equal to the number of electrons in a neutral atom.
QUESTION THREE
State whether true or false.
The smooth endoplasmic reticulum
A. Plays a role in steroid synethesis
B. Protein synethesis occurs here
C. Genetic material is found here
D. Detoxification occurs here
E. Is found in the lysosomes.
QUESTION FOUR
It is a mechanism of transport across the cell membrane and it is facilitated by the difference in pressure on the two sides of the membrane. Which mechanism is this.
A. Diffusion
B. Active transport
C. Osmosis
D. Endocytosis
E. Ultrafiltration
QUESTION FIVE
Which of the following amino acids are negatively charged.
A. Histidine
B. Glutamate
C. Proline
D. Glycine
E. Aspartate
QUESTION SIX
Renal function tests include
A. Bilirubin estimation
B. Creatnine
C. Urea
D. Glucose
E. Gamma glutaryl- transferase
QUESTION SEVEN
Urinalysis was done on a urine sample of a diabetic patient. Which of the following analytes gave a positive result.
A. Bilirubin
B. Glucose
C. Ketones
D. Urobilinogen
E. Proteins
QUESTION EIGHT
Iodine uptake test is used to ascertain the functioning of
A. Liver
B. Kidney
C. Thyroid gland
D. Adrenal gland
E. Pancreas
QUESTION NINE
Tom had a metabolic disorder that was characterized by elevated levels of uric acid. This disorder could be due to
A. Purine metabolism
B. Pyrimidine metabolism
C. Carbohydrate metabolism
D. Protein metabolism
E. Lipid metabolism
QUESTION TEN
Some common peptides include
A. Thyroxine
B. Alsosterone
C. Glutathione
D. Anti diuretic hormone
E. Oxytocin
QUESTION ELEVEN
Properties of monosaccharides include
A. They undergo enolization
B. They oxidize Benedict`s solution
C. They react with acids to form esters
D. They react with ninhydrin to give a colored product.
QUESTION TWELVE
Characteristics of a good fluid compartment marker include:
A. Should not be metabolized in the body
B. Should be colored
C. Should be non-toxic
D. Must be an organic compound
E. Should be physiologically inert.
QUESTION THIRTEEN
Endocytosis can be classified into
A. Pinocytosis
B. Exocytosis
C. Cell mediated
D. Constitutive
E. Ultrafiltration.
QUESTION FOURTEEN
Tom was diagnosed with a heart condition. Which of the following enzymes were elevated
A. Alanine aminotransferane
B. Creatine Kinase
C. Alkaline phosphatase
D. Gamma glutaryl transferase
QUESTION FIFTEEN
Some reactions seen at carboxyl terminal of the amino acids include
A. Formation of Schiff`s base
B. Decarboxylation
C. Reaction with ninhydrin
D. Esterification
E. Reduction by lithium borohydride
QUESTION SIXTEEN
Functions of the liver include:
A. Detoxification
B. Gluconeogenesis
C. Thermoregulation
D. Synethesis of insulin
E. All of the above
QUESTION SEVENTEEN
Pyrimidines include:
A. Uracil
B. Guanine
C. Thymine
D. Cytosine
E. Adenine
QUESTION EIGHTEEN
Water soluble vitamins include
A. Vitamin B2
B. Vitamin D
C. Vitamin E
D. Vitamin C
E. Folic acid
QUESTION NINETEEN
The following enzymes are used in diagnosis in the laboratory
A. Pyruvate dehydrogenase
B. Lactate dehydrogenase
C. Alkaline phosphalase
D. Aconitase
E. Gamma-glutaryl transferase
QUESTION TWENTY
Enzyme function is affected by
A. Substrate concentration
B. PH
C. Temperature
D. Availability of lipids
E. All of the above
SECTION B (Answer ALL Questions)
QUESTION ONE
What are the functions of the kidney? (5marks)
QUESTION TWO
What is the importance of carbohydrates. (3marks)
QUESTION THREE
’50% of the cell membrane is made up of proteins’. Justify this statement.
(5marks)
QUESTION FOUR
Name the types of jaundice and state clearly how each type comes about.
(5marks)
QUESTION FIVE
Differentiate between:
Type 1 and type 11 diabetes mellitus.
(2marks)
Anomers and epimers.
(2marks)
Dextrorotatory and levoratatory substances.
(2marks)
QUESTION SIX
What are the effects of vitamin ’A’ deficiency. (3marks)
QUESTION SEVEN
What does a positive nitrite test imply in urinalysis. (3marks)
SECTION C (Answer ONE Question)
QUESTION ONE
Describe how a glucose molecule is broken to yield pyruvate. (20marks)
QUESTION TWO
What are the functions of thyroid hormones. (20marks)
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