Dmls 032: Clinical Chemistry Iii Question Paper
Dmls 032: Clinical Chemistry Iii
Course:Medical Laboratory Sciences
Institution: Kenya Methodist University question papers
Exam Year:2012
KENYA METHODIST UNIVERSITY
END OF 2''ND ''TRIMESTER 2012(DAY) EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : MEDICAL LABORATORY SCIENCES
UNIT CODE : DMLS 032
UNIT TITLE : CLINICAL CHEMISTRY III
TIME : 3HOURS
INSTRUCTIONS: Answer ALL Questions in Section A and B and ONE Question in Section C
SECTION A (20marks)
QUESTION ONE
Which of the following samples is the odd one out?
A. Stool
B. Urine
C. Swab
D. Blood
QUESTION TWO
Sodium citrate was used as an anticoagulant. Which of the follow analytes cannot be checked from this sample.
A. Urea
B. Calcium
C. Uric acid
D. Cholesterol
QUESTION THREE
A urine sample was left unattended to for 6 hours. Which of the following analytes was affected.
A. Urobilinogen
B. Nitrites
C. Proteins
D. Ketones.
QUESTION FOUR
Analytical errors can be due to the following EXCEPT
A. Use of wrong wavelength
B. Improper sample collection
C. Pipetting errors
D. Use of wrong reference values.
QUESTION FIVE
Armstrong- King method is used to determine levels of
A. Urea
B. Uric acid
C. Glucose
D. Alkaline phosphatase
QUESTION SIX
Bromocresol green method is used in the estimation of the levels of
A. Glucose
B. Total proteins
C. Albumin
D. Creatnine
QUESTION SEVEN
Asatoor and king method of analysis is categorized as which method
A. Non enzymatic
B. Hormonal
C. Enzymatic
D. None of the above.
QUESTION EIGHT
Kamau had picric acid, sodium hydroxide, sodium tungstate, sulphuric acid and some appropriate standards. Which analyte levels would he determine using these reagents
A. Cholesterol
B. Glucose
C. Creatnine
D. Urea
QUESTION NINE
A patient had elevated levels of CA- 125. What cancer would this patient have.
A. Prostatic
B. Breast
C. Ovarian
D. Lung
QUESTION TEN
Which preservative is used when collecting a 24hr urine sample
A. Nitric acid
B. Hydrochloric acid
C. Sodium Bisulphite
D. Calcium carbibate
QUESTION ELEVEN
In a lipid profile, elevated levels of this analyte may be considered ’good’ which analyte is this?
A. HDL
B. LDL
C. Triglycerides
D. Cholesterol.
QUESTION TWELVE
A patient had elevated levels of acid phosphatare what condition could this patient be suffering from?
A. Liver cirrhosis
B. Pancreatitis
C. Kidney inflammation
D. Prostate cancer
QUESTION THIRTEEN
Which of the following is not a cause for elevated levels of alkaline phosphatase?
A. Teenage growth
B. Menopause
C. Pregnancy
D. Bone disease
QUESTION FOURTEEN
Alkaptonuria is caused when the body cannot break down which amino acid.
A. Alanine
B. Tyrosine
C. Glycine
D. Tryptophan.
QUESTION FIFTEEN
Elevated levels of amylase could be due to
A. Ectopic pregnancy
B. Liver cancer
C. Growth spurt
D. Breast cancer
QUESTION SIXTEEN
Iron chloride was added to urine. The urine changed colour to black. What condition was this patient suffering from?
A. Phenylketonuria
B. Glycosuria
C. Alkaptonuria
D. Diabetes mellitus.
QUESTION SEVENTEEN
Which enzyme is used in the enzymatic estimation of glucose
A. Glucose lyase
B. Glucose oxidase
C. Cholinesterase
D. Isomerase
QUESTION EIGHTEEN
Creatnine levels can be determined using
A. Asatoor and king method
B. Henry, sobel and kim method
C. Jaffe method
D. King- Armstrong method.
QUESTION NINETEEN
Which is the best anticoagulant for glucose estimation.
A. Heparin
B. Fluoride oxalate
C. None
D. EDTA
QUESTION TWENTY
Which of the following enzymes cannot be used to check liver function?
A. Creatnine Kinase
B. Alkaline phosphatase
C. Alanine transaminase
D. r glutarl transferase
SECTION B (30marks)
QUESTION ONE
What precautions can we take when collecting blood to minimize cases of hemolysis. (6marks)
QUESTION TWO
What are the functions of the cerebrospinal fluid. (4marks)
QUESTION THREE
What are the characteristics of a tumor marker. (5marks)
QUESTION FOUR
Define the blood brain barrier. (5marks)
QUESTION FIVE
State clearly causes of pre analytical errors in the laboratory. (5marks)
QUESTION SIX
Differentiate between
Phenylketonuria and alkaptonuria
(2marks)
Analytical errors and post analytical errors.
(3marks)
SECTION C
QUESTION ONE
Under what circumstances is a glucose tolerance test is done. (4marks)
What is the procedure.
(10marks)
Sketch and explain the expected results if the patient is diabetic.
(6marks)
QUESTION TWO
State THREE metabolic disorders that can arise from protein metabolism
(3marks)
What are the causes and symptom of these conditions. (17marks)
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