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Dhsci 108:Clinical Medicine Question Paper

Dhsci 108:Clinical Medicine 

Course:Diploma In Clinic Medicine

Institution: Kenya Methodist University question papers

Exam Year:2011



CLINICAL MEDICINE (DHSCI 108) 3RD TRIMESTER 2011

KENYA METHODIST UNIVERSITY

END OF 3''RD ''TRIMESTER 2011 EXAMINATIONS
FACULTY : SCHOOL OF HEALTH SCIENCES
DEPARTMENT : CLININCAL MEDECINE, SURGERY
UNIT CODE : DHSCI 108
UNIT TITLE :
TIME : 1 ½ HOURS




Instructions

Attempt all questions

1. Briefly explain the functions of plasma platelets.

2. List the types, of movement seen in GIT.

3. Write short notes on HB, MCH

4. Define the following

Tidal volume
lnspiratorv reserve volume


5. What is Homeostasis?

6. a) What is a Windkessel?

What is the physiologic significance of Windkessel effects?

7. Briefly Explain the Frank Sterling Law

8. What is the difference between the anatomic and physiological dead space s?

9. What is Chloride shift? What is its physiologic significance?
10. Outline the functions of Platelets.

SECTION B

1. Explain the functions of capillaries.

2. Explain the mechanism of fat digestion.

3. List the hormones that affect the blood glucose concentration and briefly describe
the action of each.

SECTIONC

1. . The blood vessels that play the most important role in the regulation of blood flow
to a tissue and blood pressure are the:
a. Arterioles
b. Veins
c. Capillaries
d. Venules
e. Arteries

2. The difference between the systolic and the diastolic pressures is known as the:

Blood Pressure
Pulse Pressure
Mean Arterial Pressure
End-ventricular Pressure

3. Large diameter capillaries found primarily in the liver, spleen, and bone marrow are
called:

Continuous capillaries
Fenestrated capillaries
Sinusoidal capillaries
Metarterioles
Megacapillaries

4. As you go from arteries to capillaries, the fluid pressure exerted by blood on the vessel
walls:

Increases
Decreases
Stays the same

5. The volume of blood moving through a given area in a given time is the:

Blood velocity
Blood flow
Blood pressure
Blood resistance

6. Of the following, which is the most significant factor affecting peripheral resistance?

Blood viscosity
Blood vessel length
Blood vessel radius
Blood pH

7. T lymphocytes gain immunocompetence in the:

a. Thymus

h. Thymus for T -helper cells and Bone marrow for T -killer cells

Thymus for T -killer cells and Bone marrow for T -helper cells
Bone marrow

8. Plasma cells and Helper T cells both secrete antibodies.

This statement is true
This statement is false

9. Vaccinations are an example of:

Naturally-acquired active immunity
Artificially-acquired active immunity
Naturally-acquired passive immunity
Artificially-acquired passive immune

10. The formation of an antigen-antibody complex can lead to:
I. Agglutination
II. Neutralization
III. Activation of complement

I and II only
II and III only
I and III only
d. I, II, and III

11. An example of a primary lymphoid organ in humans is the:

Thyroid
Bursa of Fabricius
Thymus
Pancreas
2 of the above are correct

12. Which of the following is NOT lymphoid organ?

Spleen
Palatine Tonsil
Thyroid
Lingual Tonsil

13. What type of epithelium would you expect to find lining the lumen of the nasal cavity?

Squamous ciliated epithelium without goblet cells
Transitional epithelium with goblet cells
Stratified squamous epithelium
Pseudostratified epithelium
None of the above

14. If John’s vital capacity is 4.5L and his tidal volume is 525cc, then what is his inspiratory
reserve volume?

3975mL
2075mL
1050mL

d. Cannot be determined from the information given

15. Total lung capacity is equal to:

Vital capacity x Tidal volume
Functional residual capacity + Expiratory reserve volume
Anatomical dead space + Alveolar dead space
Residual volume + Vital capacity

16. Most CO2 is transported in the blood in the form of:

Dissolved gas
Carbaminohemoglobin
Bicarbonate ion
Carboxyhemoglobin

17. Which of the following cells produce surfactant in lung alveoli?

Endothelial cells
Clara cells
Type I cells
Type II cells
Dust cells

18. The most powerful respiratory stimulant in a healthy person is:

Decreased tissue [oxygen]
Increased plasma PC02
Increased CSF pH
Decreased CSF Ph

19. The nose serves all the following functions except:

Passageway for air movement
Initiator of the cough reflex
Warming and humidifying inspired air
Cleansing inspired air
Providing resonance for speech production

20. Tidal volume is air:

Remaining in the lungs after forced expiration
Exchanged during normal breathing
Inhaled after quiet inspiration

. d. Forcibly expelled after normal expiration

21. The RBC count increases after an individual spends significant time at higher altitude
because:

Temperature is lower at higher altitudes
Basal metabolic rate is lower at higher altitudes
Basal metabolic rate is higher at higher altitudes
Atmospheric P02 is higher at higher altitudes
Atmospheric P02 is lower at higher altitudes

22. Most oxygen carried in the blood is:

In solution with the plasma
Combined with plasma proteins
Chemically combined with a heme group
Carried as HC03-
Bound to the amino acid valine on the beta chain of hemoglobin

23. Which of the following is not a function of the liver?

Production’ of bile
Detoxification of drugs
Storage of glucose
Storage of Vitamin C

24. The majority of the absorption of digested nutrients occurs in the:

a. Stomach
b. Ileum
c. Jejunum
d. Cecum




26.Which of the following cell types is NOT present in the stomach?

Mucous neck cells
Chief cells
Parietal cells

d. Epithelial cells

e. Alpha cells

27. Intrinsic factor is produced by which of the following cells?

Chief cells
Parietal cells
Enter endocrine cells
Parietal cells
Mucous neck cells

28. Which of the following is not a component of gastric juice?

Hydrochloric acid
Mucus
Pepsin
Amylase
Water

29. A protein molecule will be hydrolyzed by enzymes secreted from the:

Mouth, stomach, small intestine, liver
Stomach, pancreas, small intestine
Stomach, small intestine, liver
Mouth, pancreas, colon

30. Carbohydrates are acted on by:

Trypsin, chymotrypsin, and enterokinase
Amylase, maltase, and sucrose ’
Lipase
Hexokinase, pepsin, and amylase






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