Mlsc 305:Clinical Chemistry Question Paper

Mlsc 305:Clinical Chemistry 

Course:Medical Laboratory

Institution: Kenya Methodist University question papers

Exam Year:2013



CLINICAL CHEMISTRY (MEDICAL BIOCHEMISTRY) (MLSC 305) (BIOC 301) 3RD TRIMESTER 2013
KENYA METHODIST UNIVERSITY

END OF 3RDTRIMESTER 2013 (PT) EXAMINATION
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : MEDICAL LABORATORY
UNIT CODE : MLSC 305/BIOC 301
UNIT TITLE : CLINICAL CHEMISTRY (MEDICAL BIOCHEMISTRY)
TIME : 2 HOURS





INSTRUCTIONS : ''''''Answer All Questions in Section A and ANY TWO in Section B

SECTION A (30marks)

Question One
How many Mls of distilled water must be added to 5mls of a 2M Nacl solution in order to obtain a final solution of 0.1m. (5marks)

Question Two

Outline the factors considered in selecting an analytical method. (5marks)

Question Three
a) Outline the importance of thixotropic polymer gel in blood specimen
collection. (2marks)
b) Describe the mode of action of flucoride as a blood preservative.
(3marks)

Question Four
Briefly describe the factors that necessitated the introduction of automation and mention five disadvantages of automation. (5marks)

Question Five
Match the type of cancer in column A with its corresponding turnout market in column B. (5marks)


CANCER TYPE TUMOUR MARKED
Ovary CA 15 - 3
Pancrease
Colovectal TPSA
CA.125
Breast CEA
Prostrate gland CA19-9

Question Six

Describe how you would prepare a client for a creatinine clearance test.

(5marks)

SECTION B (40marks)

Question Seven
Discuss the relationship between hypothalamus and pituitary glands in hormonal productions. (20marks)

Question Eight
Discuss quality control programs in clinical chemistry. (20marks)

Question Nine

The following is an oral glucose tolerance test of a 48 year old male patient.
Time FB 9 0.5 HRS 1 HR 1.5HS 2HRS
Glucose (mmol/l) 4.4 6.8 12.5 14.7 15.9
Urine glucose NIL - PRESENT
(+++) - PRESENT
(+++)


a) Give FOUR reasons that could have warranted the request of the test.
(4marks)
b) Outline the test`s standard operating procedure. (6marks)
c) Present the above results on a graph paper. (6marks)
d) Interpret the results and justify your diagnosis. (4marks)






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