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Mbio 430:Epidemiology Question Paper

Mbio 430:Epidemiology 

Course:Applied Biology

Institution: Kenya Methodist University question papers

Exam Year:2011



KENYA METHODIST UNIVERSITY

END OF 3''RD ''TRIMESTER 2011 EXAMINATIONS
FACULTY : SCIENCE & TECHNOLOGY
DEPARTMENT : PURE & APPLIED SCIENCES
UNIT CODE : MBIO 430
UNIT TITLE : EPIDEMIOLOGY
TIME : 2 HOURS




Instructions: Answer ALL Questions in SECTION A and any TWO from

SECTION B.

SECTION A: (30 MARKS)

Question One
Explain the following approaches in epidemiology. (3 Marks)

Descriptive epidemiology
Analytic Epidemiology

Question Two
Outline the differences between incidence and prevalence as measures of morbidity. (3 Marks)

Question Three
Explain the stages in natural history of a disease. (5 Marks)

Question Four

Define case fatality rates.

(1 Mark)

(ii) In an outbreak of ebola in Goma DRC in the yar 2000, 50 people were

diagnosed to have the disease, within that year 45 of them died. What is
the case fatality rate. (3 Marks)


Question Five


Briefly explain the intrinsic host factors that influence susceptibility to a disease agent. (3 Marks)

Question Six

Use the tables below to answer questions that follow. The first table shows the number of sick persons (with acute sore throat) who ate each of the various specified combinations of the food items.

Table I: total number of persons who ate each specified combination.
Ate Tuna Did not eat Tuna
Ate egg salad 75 100
Did not eat egg salad 200 50

Table 2: Total number of persons who ate each specified combination of food items and who later became sick with acute sore throats.
Ate Tuna Did not eat Tuna
Ate egg salad 60 75
Did not eat egg salad 70 15


What is the sore throat attack rate in persons who ate both egg salad and Tuna.

(2 Marks)

According to the results in the tables which of the food items are most likely to be the infective item(s).

(2 Marks)

Question Seven
Briefly explain the following: (4 Marks)

Herd immunity
Incubation period

Question Eight
Explain the main functions of epidemiology. (4 Marks)

SECTION B: (40 MARKS)

Question One
Discuss the natural history of a disease in an individual. (20 Marks)

Question Two
Cross-sectional Studies are important in disease surveys. Explain the principles of those studies, and its various uses. (20 Marks)

Question Three
Discuss the steps taken in investigating disease outbreaks. (20 Marks)






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