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Mbio 205:Advanced Medical Microbiology Question Paper

Mbio 205:Advanced Medical Microbiology

Course:Medical Laboratory

Institution: Kenya Methodist University question papers

Exam Year:2012

KENYA METHODIST UNIVERSITY

END OF 2''ND ''TRIMESTER 2012(DAY) EXAMINATIONS
SCHOOL : MEDICINE & HEALTH SCIENCES
DEPARTMENT : MEDICAL LABORATORY SCIENCES
UNIT CODE : HSCI 205/MBIO 205
UNIT TITLE : ADVANCED MICROBIOLOGY
TIME : 3HOURS

INSTRUCTIONS: Answer ALL Questions in Section A and B and TWO Questions in Section C

SECTION A (10marks)

QUESTION ONE

Micro-organisms that cause latent infections include
A. Mycobacterium tuberculosis
B. Varicella-zoster virus
C. Cytomegalovirus (CMV)
D. Hepatitis A
E. Chlamydia trachoma

QUESTION TWO

The effect of endotoxins include:-
A. Inhibition of platelet aggregation
B. Inhibition of Hageman factor
C. Release of Interleukin 1
D. Initial leucopenia
E. Activation of the alternative complement pathuciu

QUESTION THREE

Which of the following can be used to identify staphylococcus aureus
A. Identification of lancefield groups through serology
B. Phosphatase positivity
C. Coagulase positivity
D. Fermentation of mannitol
E. Golden appearance of colonies

QUESTION FOUR

Viruses with ancogenic properties in humans include:
A. Measles virus
B. Hepatitis B virus
C. Popovavirus
D. Epstein-Barr virus
E. Cytomegalo virus

QUESTION FIVE

Aminoglycosides
A. Are active against streptococcus
B. Acts on the bacterial cell wall
C. Are useful against anaerobes
D. Should not be used in patients renal failure
E. Damages the cochlear nerve.

QUESTION SIX

Which of the following is a useful method or compound for sterilizing foods

such as fresh vegetables;
A. Ionizing radiation
B. Ultraviolet light
C. Steam autoclave
D. Phenols
E. Formaldehyde

QUESTION SEVEN

The following is INCORRECT about viral properties
A. The viral envelop contains lipoprotein
B. Viruses can replicate in non-living media
C. Viruses need live cells to grow
D. Viruses have no ribosomes
E. Viruses contain either DNA or RNA

QUESTION EIGHT

The following statement is WRONG regarding viral pathogenesis
A. Viruses spread in the body through different routes e.g. Blood, saliva
B. Humoral immunity but not cell mediated immunity acts on viruses
C. Inclusion bodies produced by viruses can be single or many.
D. Cells usually die in cytocidal infections
E. Several RNA viruses can cause persistent infection.

QUESTION NINE

The following viruses can be transmitted sexually EXCEPT
A. HIV
B. HBV
C. HSV-2
D. Adenovirus
E. Rubella virus

QUESTION TEN

The time period required for a cell to undergo binary fission is called the _____
A. Exponential growth rate
B. Germination time
C. Lag period
D. Doubling time
E. Growth curve

SECTION B

QUESTION ELEVEN
List FIVE pathogenic strains of Escherichia coli. (5marks)

QUESTION TWELVE
List FIVE herpes viruses. (5marks)

QUESTION THIRTEEN
Describe the pathogenesis of Chlamydia trachomatis. (5marks)

QUESTION FOURTEEN
Outline the economic importance of micro-organisms. (5marks)

QUESTION FIFTEEN
a) Define the term virulence. (1mark)

b) Describe FOUR types of bacterial flagella. (4marks)

QUESTION SIXTEEN
Describe the mechanism of genetic exchange in bacteria. (5marks)

QUESTION SEVENTEEN

Describe the morphology and pathogenicity of Bacillus anthracis. (5marks)

QUESTION EIGHTEEN
a) Differentiate between the terms infection and infectious disease.
(1mark)
b) Enumerate the bacteria that causes diarrhea. (4marks)

SECTION C (20marks)

QUESTION NINETEEN
a) Differentiate between sterilization and disinfection. (1mark)

b) Describe sterilization methods by moist heat. (5marks)
c) List FOUR factors that influence sterilization by heat. (4marks)

QUESTION TWENTY
Discuss the pathogenisis and treatment of treponema pallidum. (10marks)

QUESTION TWENTY ONE
Give a detailed discussion of superficial candidosis. (10marks)

Mbio 205:Advanced Medical Microbiology Question Paper

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