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Sbt 305: General Genetics Question Paper

Sbt 305: General Genetics

Course:Bachelor Of Science Microbiology And Biotechnology

Institution: University Of Nairobi question papers

Exam Year:2012

UNIVERSITY OF NAIROBI
UNIVERSITY EXAMINATIONS 2011/2012
THIRD YEAR EXAMNATIONS FOR THE DEGREE OF BACHELOR OF SCIENCE
SBT 305: GENERAL GENETICS
DATE: JANUARY 30, 2012 TIME: 9.00 AM – 12.00
INSTRUCTIONS: ANSWER ALL QUESTIONS FROM SECTIONA AND TWO SELECTED FROM SECTION B.
SECTION A
SHORT ANSWER QUESTIONS (50 minutes , 3 marks each)
1. Outline the “dark “ DNA repair mechanism.
2. Provide evidence that DNA is the genetic material.
3. In a genetics class of 50 students, 35% were found unable to taste phenylthiocarbamide. Assuming 2 alleles T and t, calculate genotypic and allelic frequencies.
4. How is expression of the lac operon controlled in E. coli?
5. Distinguish “generalized” from “specialized” transduction.
6. Explain uniparental inheritance of CO2 sensitivity in Drosophila.
7. List the steps for making Cdna.
8. What is genetic drift?
9. How does the structure of DNA compliment its functions?
10. How do reciprocal translocation between different chromosomes affect fertility?
SECTION B
1. Factors that alter genetic equilibrium.
2. Mutations that cause change in chromosome number.
3. Cytoplasmic genetic systems.
4. In peas b = brown leaves (+ = green), w = wrinkled seeds (+ = round) and y = yellow seeds (+ = plain). A cross is made between brown leaved, wrinkled seed and yellow seeded plant with the wild type. The resultant F1 progeny is test crossed to a triple recessive. The following F2 progenies were obtained.
Green Wrinkled Plain 177
Green Round Yellow 234
Green Wrinkled Yellow 10
Green Round Plain 1443
Brown Wrinkled Yellow 930
Brown Wrinkled Plain 242
Brown Round Yellow 153
Brown Round Plain 11

Sbt 305: General Genetics Question Paper

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