Clinical Pharmacology Question Paper
Clinical Pharmacology
Course:Bachelor Of Science In Medical Laboratory Science
Institution: Kenyatta University question papers
Exam Year:2009
KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2009/2010
SECOND SEMESTER EXAMINATION FOR THE DEGREE OF
BACHELOR OF SCIENCE
(MEDICAL LABORATORY SCIENCE)
HML 205: CLINICAL PHARMACOLOGY
DATE: Tuesday
22nd December 2009
TIME: 11.00am – 1.00pm
INSTRUCTIONS:
This Examination Paper contains three sections:
1.
Section A: Short Answer Questions
2.
Section B: Essay Questions
3.
Section C: Multiple Choice Questions
SECTION A: Short Answer Questions.
Attempt ALL the questions in his section (5 Marks Each)
Q.1. a)
List five pharmacokinetic parameters.
(2 ½ marks)
b)
Explain drug redistribution and give a suitable drug example.
(2 ½ marks)
Q2.
Outline the Zero order and First order kinetics of drug elimination.
(5marks)
Q3.
a)
Outline the components of an organ bath as used in isolated tissue
experiments.
(2
½
marks)
b)
Explain the use of the following equipment in pharmacological
experiments:
i)
Kymograph
(1mark)
ii)
Bull-dog
Camp [21/2 marks
SECTION B: Essay Questions.
Attempt Only One Question (20 Marks)
1
Discuss factors that affect Renal excretion.
2.
a)
Define half-life (t ½ marks) and give its importance.
(4marks)
b)
Show that half-life (t ½ marks) = 0.6909, for a mono exponential drug
K
elimination.
(10marks)
c)
Outline the characteristic of monoexponential drug eliminator.
(6marks)
SECTION C: Multiple Choice Questions
There are thirty (30) multiple Choice Questions in this Section.
Attempt ALL of them by placing a circle around the letter representing the right
answer. Each MCQ answer is equal to half (½) Mark.
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