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Ich2106:Biochemistry I Question Paper

Ich2106:Biochemistry I

Course:Bachelor Of Supplies Management

Institution: Meru University Of Science And Technology question papers

Exam Year:2013

QUESTION ONE - (30 MARKS)
a) Define the following terms; i. Ampipathic molecule (2 Marks) ii. Enzyme inhibition (2 Marks) iii. Micelle (2 Marks) b) (i) Which of the following amino acids would be most likely to be found buried in the interior of protein X and which would be more likely to be found on the proteins surface? (4 Marks)
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(ii) Give the reasons why some amino acids in protein X above are found in the interior while the others are found on the protein surface. (4 Marks) c) Give two examples of metabolic diseases. (2 Marks) d) Define essential amino acids. Give two such amino acids required in growing children. (4 Marks) e) Classify carbohydrates into 3 main types. (3 Marks) f) Give three major functions of lipids in cells (3 Marks) g) Draw and name two chemical structures of nitrogenous bases found in DNA/RNA. (4 Marks)
SECTION B
QUESTION TWO – (20 MARKS)
a) Classify amino acids into four groups depending on polarity of their side chain. (4 Marks) b) What is meant by primary structure of a protein? (2 Marks) c) Name four levels of protein structure. (4 Marks) d) What level of protein structure named in (c) above contain ? -helices and ??- sheets? (2 Marks) e) What is meant by an essential amino acid? Give two such amino acids required by growing children. (3 Marks) f) Give five functions of proteins in the body. (5 Marks)
QUESTION THREE – (20 MARKS)
a) Mutations leading to deficiencies in enzymes are usually referred to as? (2 Marks) b) Name the disease that is caused by a deficiency in the pathway below. (2 Marks) c) Name A, B, C, D and E in the pathway shown below. (5 Marks) d) Which enzyme is deficient in this disease shown in the pathway below? (2 Marks) e) List the four products in the pathway below that accumulate in blood and urine of patients. (4 Marks)
f) What is the main symptom of this disease and how can it be treated? (5 Marks)
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QUESTION FOUR – (20 MARKS)
a) Draw and label the structure of a Eukaryotic cell. (6 Marks) b) Give one function of the following molecular components of cell: (4 Marks) i. Nucleus ii. Mitochondria iii. Endoplasmic reticulum iv. Cell membrane c) Name two type of ribosomes based on their sedimentation? (2 Marks) d) Use the reaction and diagram below to answer the following question
i. Give the functional group Z on compound A. (2 Marks) ii. Identify functional group Q and compound A. (2 Marks) iii. Name the monomer represented by compound A. (2 Marks) iv. Name the type of bond formed at the arrow T above on compound B. (2 Marks)
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Ich2106:Biochemistry I Question Paper

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