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Iph2202:Medical Virology Question Paper

Iph2202:Medical Virology

Course:Bachelor Of Science In Public Health

Institution: Meru University Of Science And Technology question papers

Exam Year:2013

INSTRUCTIONS: Answer question one and any other two questions
QUESTION ONE – (30 MARKS)
(a) Describe an Icosahedral capsid. (2 Marks)
(b) Describe the cytopathic effects in cell cultures. (3 Marks)
(c) Outline three characteristics of viruses that demonstrate their difference from other life
forms. (3 Marks)
(d) Viral infections can be diagnosed by either detection of the virus or by detection of
antibodies to the virus. Outline four approaches which can be used to detect the virus or
components of the virus in animals tissues. (4 Marks)
(e) Briefly elaborate why despite intensive research, there are few drugs available for the
treatment of viral infections. (3 Marks)
(f) For each clinical scenario below, select the most appropriate treatment from the list of
options below. Each option may be used once, more than once, or not at all.
(5 Marks)
A. Inhaled zanamivir
B. Intravenous aciclovir
C. Intravenous ganciclovir
D. Oral acyclovir
2
E. Oral ganciclovir
F. Oral amantadine
G. Oral lamivudine
H. Oral ribavirin and subcutaneous interferon
I. Oral zidovudine monotherapy
J. Treatment is NOT indicated
(i) 14 pregnant women with severe chicken pox pneumonia
(ii) HIV patient with newly diagnosed bilateral cytomegalovirus retinitis
(iii) 45 year old man who is HbeAg positive and has chronic active hepatitis B
infection.
(iv) Bone marrow transplant patient with respiratory symptoms, whose
nasopharyngeal aspirate is positive for influenza B immunofluorescence
(v) 42 year old woman with chronic active hepatitis C infection confirmed by
liver biopsy.
(g) What are the three types of interferons and how is their production induced?
(3 Marks)
(h) Describe three methods by which animal viruses use to enter host cells. Give an example
of each. (3 Marks)
(i) Outline the diagnosis and prophylaxis of ??1??1 infection. (4 Marks)
QUESTION TWO – (20 MARKS)
(a) Your team needs to design a field survey to track down the characteristics of what
appears to be an emerging virus. What factors are of most concern? How do you acquire
the information and collect the needed data? (15 Marks)
(b) What is viroid? How does it differ from a virus? (2 Marks)
(c) Write short notes on delta hepatitis. (3 Marks)
QUESTION THREE – (20 MARKS)
(a) Describe the immunoprophylaxis of poliomyelitis. (4 Marks)
(b) Classify herpes viruses and give a full account of the Varicella-Zoster virus.
(16 Marks)
QUESTION FOUR – (20 MARKS)
(a) Write an essay on viral Haemorrhagic fevers. (15 Marks)
(b) Write short notes on pathology and clinical features of rotavirus infections.
(5 Marks)

Iph2202:Medical Virology Question Paper

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