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Iph2202:Medical Virology Question Paper
Iph2202:Medical Virology
Course:Bachelor Of Science In Public Health
Institution: Meru University Of Science And Technology question papers
Exam Year:2012
INSTRUCTIONS: Answer all questions in section A and B and any one question in Section C
SECTION A – 10 Marks
QUESTION ONE
The following diseases are caused by enteroviruses except which one?
a) Plerodynea
b) Glomerulonephiritis
c) Paralysis
d) Meningitis
e) Pericarditis
QUESTION TWO
The following statement is wrong about viral pathogenesis.
a) Spread of virus in the body through different routes e.g blood, saliva
b) Humoral immunity but not cell mediated immunity acts on viruses.
c) Inclusion bodies produced by viruses can be single or many
d) In cytocidal infection, cell usually die
e) Several RNA viruses can cause persistent infection
QUESTION THREE
Which of the following is WRONG about viral properties?
a) The viral envelope contain lipoprotein
b) Viruses can replicate in non-living media
c) Viruses need live cells to grow
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d) Viruses have no ribosome
e) Contain either RNA or DNA
QUESTION FOUR
Which of the following is WRONG regarding polyvirus?
a) Two vaccines are available
b) There is no vaccine for polio.
c) Can be isolated from throat or stool
d) Sub-clinical infections are common
e) Three serotypes do exist
QUESTION FIVE
The following is TRUE regarding HCV and HBV
a) HBV is dsRNA virus
b) HCV is ssRNA virus
c) Both viruses can grow in cell culture
d) HBV does not have chronic complication
e) Haemodialysis patients are at risk of HCV infections but not hemophillials.
QUESTION SIX
Which of the following viral diseases is NOT characterized by macupopular rash?
a) Measles
b) Rubella
c) Erythema infectiosum
d) Exanthema subitum
e) Herpangina
QUESTION SEVEN
Which of the following statements is NOT TRUE about herpeviruses?
a) There are eight human herps viruses
b) All are morphologically identical
c) They are all DNA viruses
d) They all cause vesicular rasj
e) All remain latent inside the human body after primary infection.
QUESTION EIGHT
The following viruses can be transmitted sexually EXCEPT?
a) HIV
b) HBV
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c) HSV-2
d) Adenovirus
e) Rubella virus
QUESTION NINE
Many antiviral drugs act by inhibition of a viral DNA polymerase enzyme. Select the virus
for which this class of drugs would be effective
a) Cytomegalovirus
b) Influenza
c) Measles
d) Mumps
e) Rabies
QUESTION TEN
The following statements regarding HIV are true EXCEPT ONE.
a) It belongs to the family retereovividae
b) It is an oncovirus
c) It is associated with the enzyme reverse transcriptase
d) The virus is present in all body fluids
e) The sexual route is the main mode of transmission
SECTION B (answer all questions – 40 Marks)
QUESTION ELEVEN
Describe the complications of the influenza virus (5 Marks)
QUESTION TWELVE
State five routes of transmission of human viruses. (5 Marks)
QUESTION THIRTEEN
List five types of herpes viruses. (5 Marks)
QUESTION FOURTEEN
Outline the pathogenesis of rubella virus (5 Marks)
QUESTION FIFTEEN
Outline the structure of a virus (5 Marks)
QUESTION SIXTEEN
Describe two mechanisms of virus latency. (5 Marks)
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QUESTION SEVENTEEN
i. List two antiviral agents that can be used for treatment of cytomegalovirus infections.
(2 Marks)
ii. List three oncogenic viruses. (3 Marks)
QUESTION EIGHTEEN
List five advantages of attenuated vaccines. (5 Marks)
SECTION C (Answer only one question)
QUESTION NINETEEN
i. Give a brief discussion of Non-nucleoside Reverse Transcriptase inhibitors (NNRTIs)
and give two examples (10 Marks)
ii. Give a brief discussion of protease inhibitors and give two examples. (10 Marks)
QUESTION TWENTY
Discuss hepatitis C virus under the following sub headings (20 Marks)
i. Pathogenesis
ii. Clinical features
iii. Treatment
QUESTION TWENTY ONE
i. Discuss the pathology of enteroviruses (10 Marks)
ii. Discuss the pathogenesis of chicken pox. (10 Marks)
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