Pmb 215: Animal Science For Biomedicine Question Paper
Pmb 215: Animal Science For Biomedicine
Course:Bachelor Of Science In Pharmaceutical Sciences
Institution: Maseno University question papers
Exam Year:2015
MASENO UNIVERSITY
UNIVERSITY EXAMINATIONS 2014/2015
SECOND YEAR SECOND SEMESTER EXAMINATIONS FOR THE
DEGREE OF BACHELOR OF SCIENCE IN PHARMACEUTICAL SCIENCES
AND MEDICAL BIOTECHNOLOGY WITH INFORMATION TECHNOLOGY
MAIN CAMPUS
PMB 215: ANIMAL SCIENCE FOR BIOMEDICINE
Date: 3rd AUGUST, 2015 2:30 - 4:30PM
INSTRUCTIONS:
.Answer ALL Questions Section A and any other TWO in section B
MASENO UNIVERSITY ISO 9001:2008 CERTIFIED
SECTION A: Answer ALL questions in section A (40 Marks)
1. a).Define "animal model" as used in biomedical research. (2 Marks)
b).Outline any three factors that should be taken into consideration in the selection of an appropriate animal model (3 Marks)
2. Briefly describe any 3 types of animal models used in biomedical research (3 Marks)
3. Name any 4 zoonotic diseases and indicate in each case the laboratory animal involved (4 Marks)
4. a).Give any two(2) reasons why mice are commonly in biomedical research? (2 Marks)
b). Explain the disadvantage(s) of using mice as a research animal (2 Marks)
5. a). Differentiate between anesthesia and euthanasia. (4 Marks)
b). List 3 instances in which euthanasia of laboratory animals is indicated (3 Marks)
6. Explain any four(4) ways by which pathogens can be introduced into laboratory animals' environment (4 Marks)
7. a)Explain the term "quarantine" as used in laboratory animal science (2 Marks)
b)Outline 5 methods that can be used to identify individual animals in an animal house (5 Marks)
8. Give reasons for using the following types of laboratory animals in biomedical research.
a)Knockout mice (2 Marks)
b)Severe combined immune deficiency(SCID) mice (2 Marks)
c)Specific Pathogen Free(SPF) animals (2 Marks)
SECTION B: Answer any TWO questions in section B (30 Marks)
9. Discuss non-experimental factors that can potentially influence the results of animal research studies (15 Marks)
10. Discuss the role of laboratory animals in biomedical research. (15 Marks)
11. Discuss the important handling and restraint techniques for the following laboratory animals
a).Rats (5 Marks)
b).Rabbits (5 Marks)
c).Mice (5 Marks)
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