Pmt 435: Prokaryotic And Eukaryotic Gene Expression Question Paper
Pmt 435: Prokaryotic And Eukaryotic Gene Expression
Course:Bachelor Of Science In Medical Biotechnology
Institution: Maseno University question papers
Exam Year:2016
MASENO UNIVERSITY
UNIVERSITY EXAMINATIONS 2016/2017
FOURTH YEAR FIRST SEMESTER EXAMINATION FOR
DEGREE OF BACHELOR OF SCIENCE IN MEDICAL BIOTECHNOLOGY
WITH INFORMATION TECHNOLOGY
MAIN CAMPUS
PMT 435: PROKARYOTIC AND EUKARYOTIC GENE EXPRESSION
Date: 3rd December, 2016 Time: 12.00-3.00pm
INSTRUCTIONS:
.Answer ALL Questions in Section A and any other TWO in Section B.
MASENO UNIVERSITY ISO 9001:2008 CERTIFIED
SECTION A(40 marks)
1. Describe the process of recombination in eukaryotic cells(5 marks)
2. Transposons are a major source of genetic mutations. Briefly comment(5 marks)
3. Organelle genomes are much smaller and have limited gene contents. Comment(5 marks)
4. Briefly describe the structure and function of spliceosomes(5 marks)
5. Suppressor mutation can lead to a functional phenotype. Briefly describe(5 marks)
6. Briefly discuss five applications of karyotyping(5 marks)
7. Write short notes on tandem repeats(5 marks)
8.B cells generate antibody diversity by alternative mRNA splicing. Describe how this process takes place(5 marks)
SECTION B(30 marks)
10.Describe the various structural organization levels of the DNA molecule in a chromosome(15 marks)
11.Discuss the processes of mRNA translation and regulation in eukaryotes(15 marks)
12.Discuss DNA damage and repair mechanisms(15 marks)
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