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Pmt 226: Medical Endocrinology Question Paper

Pmt 226: Medical Endocrinology 

Course:Bachelor Of Science In Medical Laboratory Sciences

Institution: Maseno University question papers

Exam Year:2015



MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2014/2015


SECOND YEAR SECOND SEMESTER EXAMINATIONS FOR THE
DEGREE OF BACHELOR OF SCIENCE WITH INFORMATION AND
TECHNOLOGY




MAIN CAMPUS-REGULAR




PMT 226: MEDICAL ENDOCRINOLOGY




Date:3rd AUGUST,2015 Time: 11.00-1.00pm



INSTRUCTIONS:
.Answer ALL Questions in Section A
.Answer the FIRST Question in Section B plus any other ONE from this section.






MASENO UNIVERSITY ISO 9001:2008 CERTIFIED





SECTION 1: (Short answer questions)

Answer ALL questions

1.Define the following terms, using any examples where necessary

a.Effective plasma concentration of a hormone

b.Pleiotropic effects of hormonal activity

c.Pituitary hormones without tropic functions
[2x3 marks]

2.Describe any THREE major differences between the endocrine system and the nervous system [2x3 marks]


3.Differentiate between Type I and Type II diabetes based on the synthesis and mode of activity of the hormone involved [4 marks]

4.Name TWO master endocrine glands and describe how the control endocrine system [5 marks]

5.Briefly, outline the mode of activity of prostaglandins [4 marks]

6.Briefly describe any TWO differences between hormones and enzymes [4 marks]

7.Using an appropriate example, explain how non-adrenal steroid hormones are synthesized [4 marks]

8.Describe the mode(s) of activity of oxytocin, highlighting any feedback mechanisms involved [4 marks]


9.State whether each of the following statements is TRUE or FALSE

a.It is possible to find all the hormones in a blood sample taken from the arm

b.Somatostatin is solely secreted by the D cells of the pancreas

c.Gastrin is a gastrointestinal tract (GIT) hormone that has been found to be a major mediator controlling appetite and feeding

[1x3 marks]



SECTION B: (Long answer questions)
Answer Q 10 plus any other ONE question

10.Discuss FOUR major functions of the endocrine system and explain using specific examples, how each of the functions is achieved. [20 marks]

11.Explain the two hormones feedback systems and discuss how the following hormones participates in such feedback mechanisms:
i.Estrogen
ii.Progesterone
[4+3+3 marks]

12.A patient reports to the hospital with fatigue and acute abdominal pain, which upon investigation is established to be emanating from the adrenal gland. Further examination and histology shows that the patient's skin is darkened and that some adrenal cells are damaged.

a.If the skin darkening could be the result of the hormonal imbalance, discuss in detail what leads to this manifestation.

b.Predict which zone of the adrenal gland maybe damaged and explain what can be done to resolve the hormonal imbalance
[8+2 marks]






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