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Pmt 310: Principles Of Genetics Question Paper

Pmt 310: Principles Of Genetics 

Course:Bachelor Of Science In Medical Biotechnology

Institution: Maseno University question papers

Exam Year:2013



MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2013/2014

THIRD YEAR FIRST SEMESTER EXAMINATION FOR
THE DEGREE OF BACHELOR OF SCIENCE IN
MEDICAL BIOTECHNOLOGY , MEDICAL LABORATORY SCIENCES
WITH INFORMATION TECHNOLOGY




(MAIN CAMPUS-SPECIAL EXAMS)





PMT 310: PRINCIPLES OF GENETICS





Date: 31st July,2013 Time: 2.00-4.00pm







MASENO UNIVERSITY ISO 9001:2008 CERTIFIED





SECTION A: ANSWER ALL QUESTIONS

1.Describe how PCR can be used to assay variations in a population (10 marks)

2.Define the following terms as used in genetics: a)Allele b)Homozygosity c)Heterozygosity d)Population
e)Allele frequency (10 marks)

3.Describe three(3) main methods that can be applied to determine allele frequency in a population
(10 marks)

4.Describe the 5 concepts derived from Mendel's principles (10 marks)



SECTION B: ANSWER ANY TWO QUESTIONS.( 15 MARKS EACH.)

5.Using relevant examples , describe in details how population gene/allele frequencies would be altered under the following conditions:

a)Selection against homozygosity

b)Selection against heterozygosity

6.a)Define Hardy Weinberg Principle

b)Describe the 7 conditions that a population must undergo in order to be in conformity with Herdy Weinberg Principle.

7.Using relevant examples, discuss in details Pleitropy(Genes with more than one effect) as a deviation to Mendel's principle.






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