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Pmt 422: Pharmacology And Therapeutics Question Paper

Pmt 422: Pharmacology And Therapeutics 

Course:Bachelor Of Science In Biomedical Science And Technology

Institution: Maseno University question papers

Exam Year:2010



MASENO UNIVERSITY

UNIVERSITY EXAMINATIONS 2010/2011

FOURTH YEAR SECOND SEMESTER EXAMINATIONS

FOR THE DEGREE OF BACHELOR OF SCIENCE IN BIOMEDICAL SCIENCE &
TECHNOLOGY WITH IT




MAIN CAMPUS






PMT 422: PHARMACOLOGY AND THERAPEUTICS


Date: 15th April, 2011 Time: 9.00-11.00 a.m



INSTRUCTIONS:

. This paper consists of two sections, A B.

. Answer ALL questions in SECTION A and TWO questions in SECTION B.






MASENO UNIVERSITY ISO 9001:2008 CERTIFIED


SECTION A (40 marks). Attempt ALL the questions.

1. Discuss the use of drugs in the treatment of Myasthemia gravis (10 marks)


2. Sinemet "110" is a drug combination used in the treatment of Parkinson's disease. Discuss the rationale for use Of this drug combination (10 marks)


3. Using examples, briefly discuss the clinical use and mode of action Of the following classes Of drugs:

(a)Beta 1 adrenergic receptor antagonists (5 marks).

(b) Monoamine oxidase inhibitors in the treatment of endogenous depression
(5 marks)

4. Phenytoin sodium is an anticonvulsant whose use can result in anemia. Explain this phenomenon
(10 marks).



SECTION B:

Attempt any TWO questions from this section (30 marks).

5. a) Using examples, classify local anesthetics (6 marks)

b) Discuss the mode of action of local anesthetics (6 marks)

c) Adrenaline is often used in combination with local anesthetics. Discuss the rationale for this combination. (3 marks)

6. a) Discuss the basis for the use of chlorpromazine in the treatment Of psychotic states (6 marks)

b) What are the side effects associated with chlorpromazine? (9 marks)


7. a) Discuss the clinical use and mode of action of morphine as a narcotic analgesic (9 marks).

b) What are the side effects associated with the use of narcotic analgesics?

(6 marks)






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