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Bioc 206:Introduction To Proteins And Nucleic Acids Question Paper

Bioc 206:Introduction To Proteins And Nucleic Acids

Course:Bachelor Of Science In Biochemistry

Institution: Egerton University question papers

Exam Year:2016

UNIVERSITY EXAMINATION
REGULAR-NJORO CAMPUS

FIRST SEMESTER 2016/2017
ACADEMIC YEAR

SECOND YEAR EXAMINATION FOR THE DEGREE OF BACHELOR OF SCIENCE IN BIOCHEMISTRY

BIOC 206: INTRODUCTION TO PROTEINS AND NUCLEIC ACIDS

STREAM:BSC BIOC
EXAMINATION SESSION:DECEMBER
YEAR 2016
TIME:2 HRS

INSTRUCTIONS
a)This question paper has TWO sections.SECTION A and B. Anawer ALL questions in section A and ANY ONE question in section B.
b)Do not write on the question paper

Question One
Answer the following questions in relation to proteins.
a) What is the basis of classification of amino acids? Give one example for each class of amino acid. (1+4 Marks)
b)Name two modified amino acids found in proteins and state their biological functions. (2 Marks)
Distinguish between a simple and cojugated protein. Give suitable examples. (5 Marks)

Question Two
a)Draw the structure of any amino acids as
Zwitterion
Cation form
Anion form. (1 Mark each)
b)What are the buffering groups present in a protein at physiological PH? Show how these groups help to contribute to buffering capacity. (1+2 Marks)
c)Justify the statement, "Primary structure guides the formation of secondary and tertiary structure,"give an example in support of your answer.
d)List four biologically important peptides; Give a brief account of the function of glutathione.
(1+3 Marks)
e)Compare and contrust the structural features of alpha helix and beta pleated sheets. Give examples of proteins having predominance of these structures.
(5 Marks)

Question Three
a)Outline the biological significance of nucleotides.
(5 Marks)
b) Explain the extent to which Watson-Crick structure of DNA is compatible with Chargaff's rule.
(5 Marks)
c)Differentiate between DNA and RNA. What is the implication of Uracil Presence in DNA structure?
(5 Marks)
d)Explain the hyperchromicity of denaturation of nucleic acids.
(5 Marks)
SECTION B (Total Marks:20)
Question Four
Discuss full the primary,secondary, tertiary and quatenary structure of protein.Illustrate your answer with suitable examples. (20 Marks)

Question Five
Draw the secondary forms of DNA and explain the salient features of Watson-Crick mod of double stranded structure of DNA.

Bioc 206:Introduction To Proteins And Nucleic Acids Question Paper

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