Sbc 318:Fundmentals Of Immunology Question Paper

Sbc 318:Fundmentals Of Immunology 

Course:Bachelor Of Science

Institution: Kenyatta University question papers

Exam Year:2008



KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2008/2009
FIRST SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF
SCIENCE

SBC 318:FUNDMENTALS OF IMMUNOLOGY

DATE: Friday, 5th December, 2008
TIME: 8.00 a.m. – 10.00 a.m.

SECTION A

Answer ALL the questions (10 marks each)

1.
Using, a well labeled diagram describe the structure of a lymph node.











(10 marks)

2.
A 33 year-old woman developed itching in her mouth and swelling of her lips and
tongue immediately after eating a fresh peach. She did not develop difficulty in
breathing or swallowing, and her symptoms subsided spontaneously over two
hours. She can eat tinned peaches without any problem. Explain (10 marks)

3.
How are complement pathways regulated and how do defects in regulation lead to
disease?







(10 marks)

SECTION B

Answer any TWO questions (20 marks each)

4.
Give a brief overview of the innate immune system. Discuss how innate
immunity contributes to anti-microbial immunity and how defects of innate
immunity might lead to disease.




(20 marks)

5.
Write short notes on each of the following:

a)
The immunological mechanisms underlying the action of venom
immunotherapy to treat wasp venom allergy.

(10 marks)
b)
Bacterial killing mechanisms that operate within neutrophils.
(10 marks)

6.
a)
Outline the mechanisms that generate and maintain tolerance in T cells.










(10 marks)
b)
Describe the structure of each cell of the immune system. (10 marks)








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