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Pharmacology Question Paper

Pharmacology

Course:Medicine

Institution: University Of Nairobi question papers

Exam Year:2011

1. a)Concisely describe six methods of treating Cyanide poisoning.
b)Describe the precise mechanism of action of:-
Sodium Nitroprusside

Diazoxide

Minoxidil
c)Name two pharmacologically active metabolites of Testosterone.
d)Describe the pharmacology of Radioiodine Isotype 131 including the mechanisms of action in thyrotoxicosis.
e)Name three antagonists of adrenocorticol hormone synthesis.

2. a)List four immunostimulants.
b)List 3 Calcineurin inhibitors.
c)Briefly indicate their mechanism of action.
d)Classify oral hypoglyceimic agents.
e)What is the mechanism of action of Glibenclamide?

3. a)Classify anticonvalsant drugs according to the chemical subgroups and give an example of one drug in each group.
b)Discuss the pharmacokinetics of Furosemide as a loop diuretic.
c)List 5 adverse effects of diuretics.
d)Classify lipid lowering drugs and indicate their mechanism of action.
e)Indicate adverse effect of one drug in each group.

4. a)Compare and contrast unfractionated Heparin and Low Molecular Weight Heparin.
b)List four Anti-platelet agents.
c)List the First line Anti-TB drugs.
d)Write short notes on Isoniazid.
e)Enumerate 3 adverse effects of the following:-
Pyrazinamide

Streptomycin

Rifampicin

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