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Principles Of Immunology Question Paper

Principles Of Immunology 

Course:Bachelor Of Science In Public Health

Institution: Kenyatta University question papers

Exam Year:2012



KENYATTA UNIVERSITY
UNIVERSITY EXAMINATIONS 2011/2012
SECOND SEMESTER EXAMINATION FOR THE DEGREE OF BACHELOR OF
SCIENCE (PUBLIC HEALTH)
PPH 202: PRINCIPLES OF IMMUNOLOGY
DATE: Tuesday 27th March 2012 TIME: 8.00a.m – 10.00a.m
_____________________________________________________________________________

INSTRUCTIONS
SECTION I – (20 MARKS) – ANSWER ALL QUESTIONS

1.a)List two examples of passive naturally acquired immunity.[2marks]

b)Name four antigens/pathogens that can be classified as pathogen associated
molecular patterns (PAMPs).[2marks]

c)List down the various divisions of mucosa associated lymphoid tissues (MALT)[3marks]

d)Outline the results of the binding of antibodies to the surface of host cells in Type
II hypersensitivity. [5marks]

e)Name and list the functions of five interleukins that regulate innate immunity.[5marks]

SECTION II
This has two parts. Answer all questions in part I, and any 2 in part II
PART I (20MARKS)

2.a)The skin and Mucosal Surfaces Provide Protective Barriers against Infection.
Discuss. [15marks]

b)Explain the consequences of the inflammatory agents released or produced when
one who is allergic to pollen is placed in a field of flowing maize. [5marks]

PART II (30 MARKS)

3.a)Using examples explain how FOREIGNNESS of immunogen contributes to its
immunogenicity [9marks]

b)Describe 3 examples of superantigens.[6marks]

4.a)Define the term exogenous antigen and explain how it can be recognized by the
immune system. [7marks]

b)Define the term complement and explain its functions.[4marks]

c)Draw a well labelled diagram of the model structure of an immunoglobulin. [4marks]

5.a)Discuss the functions of the following cells of the immune system.
i)Basophils [3marks]
ii)Dendritic cells [6marks]

b)Discuss the following functions of antibodies in the host defence.
i)Opsonization [3marks]
ii)Antibody-dependent cell cytotoxicity (ADCC). [3marks]






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