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•Impulse initiates release of transmitter substance acetylcholine at the end of the sensory neurone.
•Acetylcholine diffuses across the synapse and generates an impulse in the next neurone.
-The presynaptic knob have vesicles which contain transmitter substances (eg acetylcholine ) when impulses reaches synaptic knob, it stimulate the vesicles to move towards presynaptic membrane hence releasing acetyl choline, which makes the membrane permeable. The transmitter substance then diffuses across synaptic cleft to post synaptic membrane which then becomes depolarised. This causes action potential. The action potential is then transmitted as a nerve impulse along the neurone.
-Immediately afterwards, acetylcholine liberated in synaptic cleft are destroyed by an enzyme cholinesterase into choline and acetic acid which are then reabsorbed and reconstituted back to acetyl choline.
Anganifelix answered the question on April 18, 2018 at 09:33
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