Selenium is deposited in all body tissues except fat. The highest concentrations occur
in the liver, kidney, heart and spleen. Serum levels are about 0.22 µg/dl. Most
selenium in foods is bound to derivatives of the amino acids; methionine and cysteine.
Because these substances are readily absorbed, bioavailability of selenium is
considerably higher than that of zinc and iron. About 50%-100 % of dietary selenium
intake is absorbed. In addition, since no physiological mechanism appears to control
selenium absorption, selenium has a definite potential for toxicity. Most selenium is
excreted via the urine and faeces.
Functions of selenium
1. It functions as an integral component of an anti-oxidant enzyme; glutathione
peroxidase that protects cells and lipid membranes against oxidative damage.
2. It also acts as a structural component, incorporated into the protein matrix of the
teeth.
Recommended daily allowances for selenium
The recommended daily allowance estimated to be safe and adequate for an adult is
about 50-200 µg/day.
Dietary sources of selenium
Food sources vary with the selenium soil content. Good sources include sea food,
legumes, whole grains, low fat meats and dairy products with smaller amounts in
vegetables.
Selenium deficiency
The signs and symptoms of selenium deficiency include pain, muscle wasting and
cardiomyopathy, a form of heart disease.
Selenium toxicity
High doses (a milligram or above daily is toxic. Selenium toxicity causes vomiting,
diarrhoea, loss of hair and nervous system.
Titany answered the question on November 8, 2021 at 06:09
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