The phases of mitosis

1.Prophase
Prophase occupies over half of mitosis. The nuclear membrane breaks down to form a number of
small vesicles and the nucleolus disintegrates. A structure known as the centrosome duplicates
itself to form two daughter centrosomes that migrate to opposite ends of the cell. The
centrosomes organise the production of microtubules that form the spindle fibres that constitute the mitotic spindle. The chromosomes condense into compact structures. Each replicated chromosome can now be seen to consist of two identical chromatids (or sister chromatids) held together by a structure known as the centromere.

2.Prometaphase
The chromosomes, led by their centromeres, migrate to the equatorial plane in the mid-line of the cell - at right-angles to the axis formed by the centrosomes. This region of the mitotic spindle is known as the metaphase plate. The spindle fibres bind to a structure associated with the centromere of each chromosome called a kinetochore. Individual spindle fibres bind to
a kinetochore structure on each side of the centromere. The chromosomes continue to condense.

3.Metaphase
The chromosomes align themselves along the metaphase plate of the spindle apparatus.

4.Anaphase
The shortest stage of mitosis. The centromeres divide, and the sister chromatids of each
chromosome are pulled apart - or 'disjoin' - and move to the opposite ends of the cell, pulled by spindle fibres attached to the kinetochore regions. The separated sister chromatids are now referred to as daughter chromosomes. (It is the alignment and separation in metaphase and anaphase that is important in ensuring that each daughter cell receives a copy of every
chromosome.)

5.Telophase
The final stage of mitosis, and a reversal of many of the processes observed during prophase.
The nuclear membrane reforms around the chromosomes grouped at either pole of the cell, the
chromosomes uncoil and become diffuse, and the spindle fibres disappear.

6.Cytokinesis
The final cellular division to form two new cells. In plants a cell plate forms along the line of the metaphase plate; in animals there is a constriction of the cytoplasm. The cell then enters interphase - the interval between mitotic divisions.

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Titany answered the question on November 18, 2021 at 07:40